The immune system prevents diseases and infections by fighting off germs that enter the body. In some people, however, the immune system attacks healthy cells, tissues, and organs by perceiving them as a threat. This condition is known as an autoimmune disease. Experts have recognized over 80 types of autoimmune diseases that can affect any part of the human body. Generally, autoimmune diseases are incurable, with symptoms showing up in flares and requiring lifelong management. Recognizing some lesser-known autoimmune diseases To begin treatment for an autoimmune disease, it is important to get the right diagnosis. Knowing the common and lesser-known symptoms of some autoimmune diseases can help in the process. Hemolytic anemia Hemolytic anemia is an autoimmune blood condition where the body’s red blood cells are destroyed faster than they can be replaced. It may be inherited from one’s parents or acquired due to an infection, tumor, cancer, or other autoimmune disorders. Symptoms of hemolytic anemia include loss of appetite, irritability, headaches, lack of color in the skin, jaundice, dark-colored urine, fever, weakness, dizziness, confusion, fatigue, enlarged spleen and liver, tachycardia, and heart murmur. Other symptoms may also include brittle nails, pica syndrome, sore or inflamed tongue, mouth ulcers, abnormal menstrual bleeding, loss of sexual desire, and numbness in the hands and feet.